The polygon, located thirty kilometres away from Khanty-Mansiysk, was created on the basis of Yugorsk State University (YSU), which has been involved in observations of the ecosystems in the Middle Taiga region of Western Siberia since 2008. The polygon is surrounded by the ecosystems of raised bogs, dark coniferous mixed forests and floodplains of large rivers (the Ob and the Irtysh, at their confluence). The main focus of the project is the raised bog massif with a network of bridges for field work and constant monitoring equipment.

In 2011, the polygon became part of the project The International Network for Terrestrial Research and Monitoring in the Arctic: INTERACT, within the framework of which 19 research projects were implemented in the Mukhrino territory by scientists from ten countries. Since 2015, the station has been participating in the PEEX – Pan-Eurasian Experiment program bringing together over 100 research organisations in Europe, China, and Russia.